Sender Herschorn Selected Research

Muscarinic Antagonists

9/2022	Receipt of Overactive Bladder Drugs and Incident Dementia: A Population-based Case-control Study.
1/2020	Effect of mirabegron on cognitive function in elderly patients with overactive bladder: MoCA results from a phase 4 randomized, placebo-controlled study (PILLAR).
1/2020	Safety and Efficacy of Mirabegron: Analysis of a Large Integrated Clinical Trial Database of Patients with Overactive Bladder Receiving Mirabegron, Antimuscarinics, or Placebo.
6/2018	A strategy utilizing ambulatory monitoring and home and clinic blood pressure measurements to optimize the safety evaluation of noncardiovascular drugs with potential for hemodynamic effects: a report from the SYNERGY trial.
10/2017	Characteristics of antimuscarinic responders versus suboptimal responders in a randomized clinical trial of patients with overactive bladder symptoms.
5/2017	Cardiovascular safety in refractory incontinent patients with overactive bladder receiving add-on mirabegron therapy to solifenacin (BESIDE).
1/2016	Efficacy and Safety of Mirabegron Add-on Therapy to Solifenacin in Incontinent Overactive Bladder Patients with an Inadequate Response to Initial 4-Week Solifenacin Monotherapy: A Randomised Double-blind Multicentre Phase 3B Study (BESIDE).
8/2015	The efficacy and safety of mirabegron compared with solifenacin in overactive bladder patients dissatisfied with previous antimuscarinic treatment due to lack of efficacy: results of a noninferiority, randomized, phase IIIb trial.
12/2014	Onset of action of the β3-adrenoceptor agonist, mirabegron, in Phase II and III clinical trials in patients with overactive bladder.
5/2014	Do patient characteristics predict responsiveness to treatment of overactive bladder with antimuscarinic agents?

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Sender Herschorn Research Topics

Disease

44	Overactive Urinary Bladder (Overactive Bladder) 09/2022 - 12/2004
23	Urinary Incontinence 01/2022 - 05/2006
18	Prostatic Neoplasms (Prostate Cancer) 03/2021 - 06/2002
9	Stress Urinary Incontinence 01/2021 - 01/2004
8	Urinary Retention 01/2021 - 05/2006
8	Neoplasms (Cancer) 10/2020 - 02/2014
6	Constipation 10/2017 - 05/2006
4	Pathologic Constriction (Stenosis) 01/2022 - 03/2014
4	Lower Urinary Tract Symptoms 01/2021 - 09/2009
3	Spinal Cord Injuries (Spinal Cord Injury) 01/2022 - 06/2011
3	Multiple Sclerosis 01/2022 - 06/2011
3	Myocardial Infarction 01/2021 - 01/2016
3	Prostatic Hyperplasia (Benign Prostatic Hyperplasia) 01/2021 - 05/2015
3	Urinary Tract Infections (Urinary Tract Infection) 01/2020 - 04/2013
2	Hydronephrosis 01/2022 - 01/2021
2	Wounds and Injuries (Trauma) 11/2021 - 01/2010
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 10/2017
2	Headache (Headaches) 01/2020 - 04/2013
2	Cardiovascular Diseases (Cardiovascular Disease) 04/2018 - 01/2018
2	Nocturia 10/2017 - 09/2013
2	Dyspepsia (Indigestion) 10/2017 - 05/2006
2	Hypertension (High Blood Pressure) 05/2017 - 04/2013
2	Erectile Dysfunction 01/2015 - 02/2014
2	Prolapse 06/2012 - 11/2007
2	Dizziness (Lightheadedness) 08/2007 - 05/2006
1	Dementia (Dementias) 09/2022
1	Urinary Bladder Calculi (Bladder Calculi) 02/2022
1	Angina Pectoris 01/2021
1	Solitary Kidney 01/2021
1	Cerebral Infarction 01/2021
1	Lacunar Stroke 01/2021
1	Sarcoma (Soft Tissue Sarcoma) 10/2020
1	Diarrhea 01/2020
1	Cognitive Dysfunction 01/2020
1	Cardiac Arrhythmias (Arrythmia) 10/2019
1	Infections 01/2019
1	Atrial Fibrillation 10/2018
1	Bladder Exstrophy (Exstrophy, Bladder) 04/2018
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2018
1	Hematuria 10/2017
1	Tachycardia (Tachyarrhythmias) 05/2017
1	Coronary Disease (Coronary Heart Disease) 11/2016
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 11/2016
1	Rectal Neoplasms (Rectal Cancer) 03/2016
1	Second Primary Neoplasms (Neoplasms, Second) 03/2016
1	Stroke (Strokes) 01/2016
1	Interstitial Cystitis (Interstitial Cystitis, Chronic) 03/2015
1	Contracture 11/2014
1	Urethral Stricture 03/2014

Drug/Important Bio-Agent (IBA)

26	mirabegronIBA 09/2022 - 04/2013
15	Solifenacin Succinate FDA Link 09/2022 - 05/2010
12	Muscarinic AntagonistsIBA 09/2022 - 05/2010
11	Tolterodine Tartrate (Detrol)FDA Link 09/2022 - 05/2006
9	Cholinergic Antagonists (Anticholinergics)IBA 09/2022 - 12/2004
7	fesoterodine FDA Link 09/2022 - 01/2010
7	Type A Botulinum Toxins (Botox)FDA Link 01/2017 - 06/2011
6	Pharmaceutical PreparationsIBA 09/2022 - 12/2014
4	Adrenergic Receptors (Adrenergic Receptor)IBA 08/2018 - 08/2013
2	oxybutynin (Tavor)FDA LinkGeneric 09/2022 - 05/2010
2	Tamsulosin (Flomax)FDA LinkGeneric 01/2021 - 01/2020
2	Prostate-Specific Antigen (Semenogelase)IBA 10/2020 - 11/2010
2	TabletsIBA 10/2018 - 09/2013
2	AndrogensIBA 01/2018 - 11/2016
2	Biological ProductsIBA 06/2012 - 11/2007
2	baysilon (polydimethylsiloxane)IBA 04/2010 - 01/2009
1	darifenacin FDA Link 09/2022
1	ORALIT (ORS)IBA 09/2022
1	abobotulinumtoxinA FDA Link 01/2022
1	Triamcinolone Acetonide (Azmacort)FDA LinkGeneric 03/2021
1	Triamcinolone (Aristocort)FDA Link 03/2021
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	insulin receptor-related receptor (IRR)IBA 10/2017
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 10/2017
1	AnticoagulantsIBA 10/2017
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 10/2017
1	Testosterone (Sustanon)FDA Link 01/2016
1	Tadalafil (Cialis)FDA Link 05/2015
1	Pentosan Sulfuric Polyester (Pentosan Polysulfate)FDA Link 03/2015

Therapy/Procedure

15	Therapeutics 01/2021 - 06/2002
13	Radiotherapy 01/2019 - 06/2002
12	Prostatectomy (Retropubic Prostatectomy) 03/2021 - 02/2012
4	Injections 01/2022 - 01/2005
4	Drug Therapy (Chemotherapy) 10/2020 - 04/2013
4	Suburethral Slings (Tension-Free Vaginal Tape) 11/2014 - 02/2012
3	Artificial Urinary Sphincter 01/2019 - 11/2014
3	Aftercare (After-Treatment) 01/2019 - 03/2014
2	Catheters 01/2021 - 01/2021
2	Duration of Therapy 09/2016 - 01/2016
2	Brachytherapy 03/2016 - 03/2014
1	Local Anesthesia 02/2022
1	Length of Stay 01/2022
1	Stents 11/2021
1	Nephrotomy 01/2021
1	Bathroom Equipment 01/2020
1	Prostheses and Implants (Prosthesis) 01/2019
1	Transitional Care 04/2018
1	Polypharmacy 01/2017
1	Ambulatory Care (Outpatient Care) 01/2016
1	Percutaneous Nephrolithotomy 01/2015
1	Urinary Diversion (Ileal Conduit) 03/2014